Art History is at the brink of new ways of accessing its material and gaining unprecedented insights. While we are still using image databases that resemble slide libraries, Information Science has to offer multiple advanced approaches to images, such as content based search and classification that will become important tools for art historical research. Big Image Data will enable us to master the content of huge collections by making use of intelligent algorithms and visualizing their results. What requirements does Art History have towards Information Technology? What projects do exist that can serve as best practice? Which direction does Art History go from here?